Special Feature
Comparative effectiveness of two pharmacy-based colorectal cancer screening interventions during an annual influenza vaccination campaign
Michael B. Potter, MD; Ginny Gildengorin; Yinan Wang; May Wu; Lisa Kroon, PharmD
J Am Pharm Assoc (2003) 2010;50:181-187. doi:10.1331/JAPhA.2010.09199


Objective  To compare the effectiveness of two different pharmacy-based colorectal cancer screening (CRCS) interventions taking place during an annual influenza vaccination campaign.

Design  Time-randomized clinical trial.

Setting  San Francisco, CA, in late 2008.

Participants  133 adults aged 50 to 80 years visiting a pharmacy during an influenza vaccination campaign and also due for CRCS.

Intervention  On five dates, eligible patients were provided education and encouraged to obtain screening from their primary care clinician. On 17 dates, a home fecal immunochemical test (FIT) for CRCS was provided. A 16-item questionnaire was administered by phone 3 to 6 months after study enrollment.

Main outcome measure  Self-reported CRCS activity, comparing CRCS completion rates for participants provided with the FIT versus those provided with education and encouragement to obtain screening from patients' primary care clinician.

Results  86 participants in the FIT arm and 28 the CRCS education arm were interviewed. Interviews revealed that 19.8% of the FIT group and 50% of the CRCS education group discussed CRCS with their primary care clinician (P = 0.002). Of these participants, 59.3% in the FIT arm and 14.8% in the CRCS education arm reported completing screening (P < 0.001). Of participants in the FIT group, 52.2% completed FIT dispensed to them by the investigators. Most participants in both groups reported interest in receiving CRCS education and home CRCS tests from pharmacists in the future.

Conclusion  Pharmacy patients are receptive to CRCS interventions delivered in community pharmacies. Providing FIT to eligible patients during a pharmacy-based influenza vaccination campaign increases screening rates more than CRCS education alone.

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Walsh JM, Terdiman JP. Colorectal cancer screening: Scientific review JAMA. 2003;289:1288–96.[PubMed][CrossRef]
 Centers for Disease Control and Prevention. Use of colorectal cancer tests: United States, 2002, 2004, 2006 MMWR Morb Mortal Wkly Rep. 2008;57:253–8.[PubMed]
 American Cancer Society. Cancer facts and figures 2009. Accessed at www.cancer.org/downloads/STT/500809web.pdf, August 1,  2009.
 U.S. Preventive Services Task Force. Screening for colorectal cancer: U.S. Preventive Services Task Force Recommendation Statement Ann Intern Med. 2008;149:627–37.[PubMed]
Zauber AG, Lansdorp-Vogelaar I, Knudsen AB, et al. Evaluating test strategies for colorectal cancer screening: A decision analysis for the U.S. Preventive Services Task Force Ann Intern Med. 2008;149:680–2.[PubMed]
Allison JE, Potter MB. New screening guidelines for colorectal cancer: A practical guide for the primary care physician Prim Care. 2009;36:575–602.[PubMed]
Howard K, Salkeld G. Home bowel cancer tests and informed choice: Is current information sufficient? Aust N Z J Public Health. 2003;27:513–6.[PubMed]
Prosser LA, O’Brien MA, Molinari NA, et al. Non-traditional settings for influenza vaccination of adults: Costs and cost effectiveness Pharmacoeconomics. 2008;26:163–78.[PubMed]
Kamal KM, Madhavan SS, Maine LL. Pharmacy and immunization services: Pharmacists’ participation and impact J Am Pharm Assoc. 2003;43:470–82.
Goode JR, Mott DA, Stanley DD. Assessment of an immunization program in a supermarket chain pharmacy J Am Pharm Assoc. 2007;47:495–8.
Van Amburgh JA, Waite NM, Hobson EH, Migden H. Improved influenza vaccination rates in a rural population as a result of pharmacist-managed immunization campaign Pharmacotherapy. 2001;21:1115–22.[PubMed]
Hogue MD, Grabenstein JD, Foster SL, Rothholz MD. Pharmacist involvement with immunizations: A decade of professional advancement J Am Pharm Assoc. 2006;46:168–79.
Potter MB, Phengrasamy L, Hudes ES, et al. Offering annual fecal occult blood tests at annual flu shot clinics increases colorectal cancer screening rates Ann Fam Med. 2009;7:17–23.[PubMed]
 American Association of Colleges of Pharmacy. Center for Advancement in Pharmaceutical Education: Educational outcomes 2004. Accessed at www.aacp.org/resources/education/Documents/CAPE2004.pdf, October 16,  2009.
 Royal Pharmaceutical Society of Great Britain. The public's use of community pharmacies as a primary health care resource. Accessed at www.rpsgb.org.uk/pdfs/cprc.pdf, August 17,  2009.
Baier M, Calonge N, Cutter G, et al. Validity of self-reported colorectal cancer screening behavior Cancer Epidemiol Biomarkers Prev. 2000;9:229–32.[PubMed]
Hall HI, Van Den Eeden SK, Tolsma DD, et al. Testing for prostate and colorectal cancer: Comparison of self-report and medical record audit Prev Med. 2004;39:229–32.
Partin MR, Grill J, Noorbaloochi S, et al. Validation of self-reported colorectal cancer screening behavior from a mixed-mode survey of veterans Cancer Epidemiol Biomarkers Prev. 2008;17:768–76.[PubMed]
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