Research Notes
Discordance between ambulatory care clinic and community pharmacy medication databases for HIV-positive patients
Christie A. Robinson, PharmD, BCPS; Jennifer Cocohoba, PharmD; Conan MacDougall, PharmD, BCPS; Malcolm D.V. John, MD, MPH; B. Joseph Guglielmo, PharmD
J Am Pharm Assoc (2003) 2007;47:613-615. doi:10.1331/JAPhA.2007.06131


Adverse drug events (ADEs) are a major cause of morbidity in the primary care setting.+1 Patients with medical conditions that require multiple medications experience more ADEs and drug-related morbidity and mortality than patients taking fewer medications.+2,+3 More than 50% of hospital admissions secondary to medication-associated problems are potentially preventable.+4 Treatment of HIV infection is generally associated with a large pill burden as a result of combination medication regimen use for highly active antiretroviral therapy.+5,+6

First Page Preview

View Large
First page PDF preview
Sign In
APhA Members 
Welcome to JAPhA.org! Please log in below using your APhA username and password. Update your APhA profile.
Not a Subscriber
New to JAPhA? Become an APhA member to receive a full subscription to both the print and online editions.


Register for a FREE limited account to benefit from personalization features such as alerts.


Avery AJ, Sheikh A, Hurwitz B, et al. Safer medicines management in primary care.  Br J Gen Pract.  2002;52(suppl):S17–22.[PubMed]
Nguyen JK, Fouts MM, Kotabe SE, et al. Polypharmacy as a risk factor for adverse drug reactions in geriatric nursing home residents.  Am J Geriatr Pharmacother.  2006;4:36–41.[PubMed][CrossRef]
Frazier SC. Health outcomes and polypharmacy in elderly individuals: an integrated literature review.  J Gerontol Nurs.  2005;31:4–11.[PubMed]
Winterstein AG, Sauer BC, Hepler CD, Poole C. Preventable drug-related hospital admissions.  Ann Pharmacother.  2002;36:1238–48.[PubMed]
 DHHS Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for using antiretroviral agents among HIV-1-infected adults and adolescents. Accessed at http://aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf, November 6,  2006.
 U.S. Public Health Service, Infectious Diseases Society of America. Guidelines for the preventing opportunistic infections among HIV-infected persons: 2002. Accessed at http://aidsinfo.nih.gov/ContentFiles/OIpreventionGL.pdf, November 6,  2006.
Ernst ME, Brown GL, Klepser TB, et al. Medication discrepancies in an outpatient electronic medical record.  Am J Health Syst Pharm.  2001;58:2072–5.[PubMed]
Wagner MM, Hogan WR. The accuracy of medication data in an outpatient electronic medical record.  J Am Med Inform Assoc.  1996;3:234–44.[PubMed]
de Maat MMR, de Boer A, Koks CHW, et al. Evaluation of clinical pharmacist interventions on drug interactions in outpatient pharmaceutical HIV-care.  J Clin Pharm Ther.  2004;29:121–30.[PubMed]
Kaboli PJ, McClimon BJ, Hoth AB, Barnett MJ. Assessing the accuracy of computerized medication histories.  Am J Manag Care.  2004;10:872–7.[PubMed]
Manley HJ, Drayer DK, McClaran M, et al. Drug record discrepancies in an outpatient electronic medical record: frequency, type, and potential impact on patient care at a hemodialysis center.  Pharmacotherapy.  2003;23:231–9.[PubMed]
Korthuis PT, Asch S, Mancewicz M, et al. Measuring medication: do interviews agree with medical record and pharmacy data?  Med Care.  2002;40:1270–82.[PubMed]
Bedell SE, Jabbour S, Goldberg R, et al. Discrepancies in the use of medications: their extent and predictors in an outpatient practice.  Arch Intern Med.  2000;160:2129–34.[PubMed]
Price D, Cooke J, Singleton S, Feely M. Doctors' unawareness of the drugs their patients are taking: a major cause of overprescribing? Br Med J (Clin Res Ed).  1986;292:99–100.[PubMed]
Monson RA, Bond CA. The accuracy of the medical record as an index of outpatient drug therapy.  JAMA.  1978;240:2182–4.[PubMed]
de Maat MMR, Frankfort SV, Mathôt RAA, et al. Discrepancies between medical and pharmacy records for patients on anti-HIV drugs.  Ann Pharmacother.  2002;36:410–5.[PubMed]
Royal S, Smeaton L, Avery AJ, et al. Interventions in primary care to reduce medication related adverse events and hospital admissions: systematic review and meta-analysis.  Qual Saf Health Care.  2006;15:23–31.[PubMed]
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Please read the other comments before you post yours. Comments are moderated and will appear on the site at the discertion of the editorial staff.
* = Required Field
(if multiple authors, separate names by comma)
Example: John Doe

Related Content

Customize your page view by dragging & repositioning the boxes below.

JAPhA Articles
Topic Collections
  • Print
  • PDF Download
  • Email
  • Share
  • Get Citation
  • Submit Comment
  • Article Alerts
    Please Wait... Processing your request... Please Wait.
    You must sign in to sign-up for alerts.

    Please confirm that your email address is correct, so you can successfully receive this alert.

  • Letters To Editor
  • Reprints